Theranostics in breast cancer

Introduction Breast cancer is a complex disease which constitutes the leading cause of in women globally. Conventional treatment modalities include surgery, chemotherapy, radiation therapy, and hormonal therapy; all have their limitations often result significant side effects or toxicity. Targeted radionuclide therapy based on theranostic approach, has been successfully applied several malignancies, such as prostate cancer, thyroid neuro-endocrine tumours. Several studies highlighted potential applications also breast cancer. Aim This review aims to provide an overview most promising current- future approaches Discussion The discussion includes pre-clinical well clinical data some successful targets used date. Examples those targeting HER-2 expression, angiogenesis, aspects tumour microenvironment, GRPr-, PSMA- CXCR-4 expression. challenges widespread implementation remain, regulatory approval, access various radiopharmaceuticals imaging technology, cost-effectiveness, absence robust data. Conclusion Theranostic greatly improve diagnosis, treatment, outcomes for patients with More research needed fully explore identify best targets, considering feasibility, costs, efficacy, outcomes.